针对天然产物中的主要活性成分,基于现代色谱技术构建其提取分离纯化方法,开发其制备工艺。采用真菌、生物酶等媒介制备活性天然化合物及其结构类似物,并开发其系统的制备方法。

Reference
(1) Efficiently regioselective glucosylation of estrogen analogues mediated by fungus (2) Rhizopus oryzae AS 3.2380.Catalysis Communications, 2017, 97, 106–110.
Highly regioselective glucosylation of alcoholic hydroxyls of protostane triterpenoids mediated by fungal biotransformation. Catalysis Communications, 2017, 89, 40–43.